• Tentang UGM
  • Portal Akademik
  • IT Center
  • Perpustakaan
  • Webmail
  • Dies 74
  • Bahasa IndonesiaBahasa Indonesia
    • Bahasa IndonesiaBahasa Indonesia
    • EnglishEnglish
Universitas Gadjah Mada Fakultas Kedokteran Gigi
Universitas Gadjah Mada
  • Tentang FKG
    • Visi, Misi, dan Tujuan
    • Sejarah
    • Daftar Dosen
    • Daftar Pejabat
    • Gallery
  • Pendidikan
    • Program Sarjana dan Profesi Program Studi Pendidikan Dokter Gigi
    • Program Sarjana Program Studi Higiene Gigi
    • Program Studi S2
      • Program Magister S2 Program Studi Ilmu Kedokteran Gigi
      • Program MagisterProgram StudiIlmu Kedokteran Gigi Klinik
    • Program Studi S3
      • Program Doktor Program StudiIlmu Kedokteran Gigi
    • Program Pendidikan Dokter Gigi Spesialis (PPDGS)
      • Program Studi Spesialis Prostodonsia
      • Program Studi Spesialis Kedokteran Gigi Anak
      • Program Studi Spesialis Konservasi Gigi
      • Program Studi Spesialis Bedah Mulut dan Maksilofasial
      • Program Studi Spesialis Periodonsia
      • Program Studi Spesialis Ortodonsia
  • Departemen
    • Departemen Prostodonsia
    • Departemen Radiologi Dentomaksilofasial
    • Departemen Biologi Oral
    • Departemen Ilmu Penyakit Mulut
    • Departemen Ilmu Kedokteran Gigi Anak
    • Departemen Biomedika Kedokteran Gigi
    • Departemen Biomaterial Kedokteran Gigi
    • Departemen IKGP dan IKGM
    • Departemen Periodonsia
    • Departemen Ortodonsia
    • Departemen Ilmu Konservasi Gigi
    • Departemen Bedah Mulut dan Maksilofasial
  • Penelitian
    • KERANGKA ACUAN KEGIATAN DAMAS 2022
    • Prisma LPPM
    • SIM Publikasi FKG UGM
    • Majalah Kedokteran Gigi Indonesia
    • The Indonesian Journal of Dental Research
    • Majalah Kedokteran Gigi Klinik
    • Panduan Laporan Hibah Penelitian Dosen
  • Unit Pendukung
    • Unit Jaminan Mutu
      • BAN-PT Program Sarjana 2010
      • BAN PT Program Sarjana & Profesi 2015
    • Unit Pengabdian Masyarakat
      • SOP Pengabdian Masyarakat
      • Form Laporan Pengabdian
    • Unit Bimbingan Konseling
    • Unit Etika dan Advokasi
      • Pengurusan Kelayakan Etik Penelitian
      • Formulir Penilaian Etika Penelitian Dengan Subyek Hewan
      • Formulir Penilaian Etika Penelitian Dengan Subyek Manusia
      • Formulir Penilaian Etika Penelitian Dengan Subyek Mikroba/Material
      • Kelengkapan Berkas Mengajukan Ethical Clearance (EC)
    • Unit Perpustakaan
    • Unit Publikasi
    • Unit Teknologi Informasi dan Humas
    • Unit Layanan Pengadaan dan Sarana Prasarana
    • Unit Laboratorium Riset Terpadu
    • Unit Pengembangan Usaha
  • Tautan
    • Portal Pegawai Simaster
    • InEMS
    • Akademika
    • Blog UGM
    • Simpan UGM
    • Kamus Online
    • Multimedia UGM
    • Dikti
    • E-Learning
    • Surveilans Riset
  • Beranda
  • Program Studi
  • Departemen Biomedika Kedokteran Gigi

Departemen Biomedika Kedokteran Gigi

  • Program Studi
  • 9 Juli 2010, 09.18
  • Oleh: admin
  • 0

Department of Dental Biomedical Sciences

Our department learning and research activities focus on general to molecular understanding of the mechanism of diseases. The basic knowledge on the disease mechanism is very important to support new strategy for regenerative medical and dental therapies, including tissue engineering and drug delivery system. The following is the overview of the researches which have been being done in our department.

Identification of Sp6 target gene in dental epithelial cells

To develop regeneration therapy in the clinical treatment, we need to understand the developmental events at molecular levels. Although the profiles of gene expression are well-documented during tooth development and morphogenesis, the molecular mechanism of their regulations remains to be determined. In view of this, Sp6, a wherein Sp6 mRNA is expressed in a tissue-specific manner duringdevelopment, i.e., hair follicle, limb bud, and tooth germ. To investigate a possible role in tooth development, Sp6-overproducing clone is established and genome-wide screening of Sp6 target genes is performed. It has been identified that genes is performed. It has been identified that follistatin gene is one of the Sp6 target genes. Meanwhile, Sp6-mediated inhibition of the follistatin gene expression is suggested to be regulated at the transcriptional level. A role of Sp6 in amelogenesis is proposed through the down-regulation of the follistatin gene expression during tooth development and morphogenesis.

Inflammation induction by ligation of submandibular gland

In this dtudy, ligation of submandibular gland was done to induce inflammation. It is know from the study that stem cell antigen-I (Sca-I) expression increased by the ligation. The increase of Sca-I expression was due to the pro-inflammatory cytokine named IL-6 which induces STAT3 phosphorilation of Tyr705 through JAK-STAT and ERK I/2 pathways. On the next mechanism, P-STAT3 (Tyr705) bound to GAS element at Sca-I promoter region to induce Sca-I expression.

Hard tissue regenerative therapy by applying tissue engineering technology

Despite four decades of extensive efforts to provide bone substitutes, synthetic bone substituting materials are still largely inferior to auto- or allografts as the gold standard in orthopedic and dental surgery. The clinical success of the current generation of bone substituting methods is limited, since they lack the high functionality of bone tissue in terms of biological and mechanical properties. In our laboratory, matrices for bone repair to mimic nanostructure of bone are developed by applying tissue engineering technology which combines scaffold, growth factors, and cells. We have been trying to synthesize biomimetic structure with a nanodispersed mineral phase to provide structure for organizing dissociated cells into appropriate tissue construction by creating an environment that enables 3-D cell growth and neo-tissue formation (DOI: 10.1016/j.actabio.2009.09.005).

Search

Admission for International Programs

Universitas Gadjah Mada

FAKULTAS KEDOKTERAN GIGI

Universitas Gadjah Mada

Jl.Denta 1, Sekip Utara,Yogyakarta 55281 Indonesia

 fkg@ugm.ac.id
+62 274 515307

Akademik
Panduan Akademik
Competencies of Graduates In The Professional Study Program
Download
KAK Hibah Pengembangan Video Pembelajaran
Sertifikat Akreditasi LAMPTKES
KAK Hibah Penelitian DAMAS 2020
Format Laporan Kemajuan DAMAS
Tautan Luar
Badan Kepegawaian Negara
PDDIKTI

Informasi

  • RSGM Prof. Soedomo
  • Beasiswa
  • Lowongan
  • Pedoman Tendik Berprestasi

Sertifikat BAN PT

  • Sertifikat BAN PT FKG UGM
  • BAN PT Program Studi Sarjana Kedokteran Gigi 2019
  • BAN PT S1 PDG 2015
  • BAN PT Program Studi Sarjana Higiene Gigi 2019
  • BAN PT Program Profesi 2019
  • BAN PT Profesi DRG 2015
  • BAN PT Program Doktor
  • BAN PT Program Pasca Sarjana
  • Akreditasi Prodi S3 IKG

Format Proposal

  • Hibah Pengembangan Video Pembelajaran FKG UGM 2020

© 2017 Fakultas Kedokteran Gigi Universitas Gajah Mada

KEBIJAKAN PRIVASI/PRIVACY POLICY