{"id":20609,"date":"2026-07-17T10:50:51","date_gmt":"2026-07-17T03:50:51","guid":{"rendered":"https:\/\/fkg.ugm.ac.id\/?p=20609"},"modified":"2026-07-17T10:50:53","modified_gmt":"2026-07-17T03:50:53","slug":"ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan","status":"publish","type":"post","link":"https:\/\/fkg.ugm.ac.id\/en\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/","title":{"rendered":"When the Dental Pulp of Primary Teeth Holds the Key to Tissue Regeneration"},"content":{"rendered":"<p class=\"wp-block-paragraph translation-block\">Stem cells from children\u2019s primary dental pulp harbor molecular mechanisms that are far more complex than previously thought. A study published in Experimental and Therapeutic Medicine in 2021 revealed a surprising finding: fibroblast growth factor 2 (FGF2), a growth factor long known to play an important role in tooth development and dentin repair, can suppress the expression of the inflammatory cytokine CCL11 through a specific signaling pathway in human dental pulp-derived mesenchymal stem cells. One of the researchers involved in the molecular analysis was drg. Anrizandy Narwidina, MDSc, Sp.KGA, Ph.D., an academic staff member of the Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Gadjah Mada.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Stem Cells from a Shed Tooth<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A shed primary tooth is more than just a childhood keepsake. The pulp tissue inside it contains mesenchymal stem cells that are relatively easy to isolate compared with stem cells from other sources, such as bone marrow or adipose tissue. This advantage makes stem cells derived from deciduous dental pulp an attractive candidate for the development of regenerative therapies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In this study, a research team from Tokushima University and Tokyo Medical and Dental University used the SDP11 cell line, which had previously been isolated from the primary teeth of three healthy children aged 6\u20138 years. The cells were then exposed to FGF2 at various concentrations and for different durations, after which cytokine expression was analyzed using PrimerArray-based RT-qPCR, which simultaneously examines 88 cytokine genes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The results were unexpected. Among all the cytokines detected in the SDP11 cells, only CCL11 was consistently suppressed by FGF2 in both a time- and dose-dependent manner. Significant suppression began after 12 hours of exposure and at an FGF2 concentration of at least 10 ng\/mL.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>CCL11: An Inflammatory Cytokine That Is Also Linked to Aging<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CCL11, also known as eotaxin, is no ordinary cytokine. It is a specific chemoattractant for eosinophils and plays a role in inflammatory and allergic conditions such as asthma. Moreover, elevated CCL11 levels in the plasma and cerebrospinal fluid of aged animals have been associated with reduced neurogenesis, placing CCL11 among the factors linked to biological aging.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In dental tissue, another study cited by the researchers found that administering antibodies that suppress CCL11 can enhance pulp regeneration by reducing the number of M1 macrophages\u2014the inflammatory type\u2014and improving the M1\/M2 ratio. In other words, controlling CCL11 is not merely about reducing inflammation; it may also pave the way for more effective tissue regeneration.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>\u201cThese findings indicate that FGF2 regulation of CCL11 expression through dental pulp-derived mesenchymal stem cells has anti-inflammatory effects and supports tissue regeneration.\u201d<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This statement captures the central implication of the study, emphasizing that FGF2 is not merely a factor that promotes cell proliferation but also a modulator of the inflammatory microenvironment surrounding stem cells.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>The JNK Pathway: The Key Among Three Signaling Pathways<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The most intriguing aspect of the study lies in the identification of the signaling pathway responsible for this effect. FGF2 is known to activate several MAPK pathways, including p38 MAPK, ERK1\/2, and JNK (c-Jun N-terminal kinase). The question was: which pathway mediates the suppression of CCL11?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The researchers tested all three pathways using specific inhibitors. When the JNK inhibitor SP600125 was administered, FGF2-mediated suppression of CCL11 was completely abolished. In contrast, the p38 MAPK inhibitor SB203580 and MEK\/ERK inhibitor U0126 did not produce a similar effect.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The conclusion was clear: the FGF2\/FGFR\/JNK pathway specifically mediates the suppression of CCL11 expression in human dental pulp-derived mesenchymal stem cells. According to the researchers, this was the first such finding reported in the context of dental pulp-derived stem cells.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>From Cell Experiments to the Clinic: A Long Road Ahead<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">The researchers openly acknowledged the limitations of the study. The use of a cell line as a model of human mesenchymal stem cells has limitations compared with primary cell cultures or live animal models. Further validation using in vivo models is still required before these findings can be translated into clinical applications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Nevertheless, the molecular map generated by this study provides an important foundation. Understanding how FGF2 modulates the cytokine environment surrounding dental pulp stem cells opens new possibilities for designing pulp regeneration therapies, particularly for patients with chronic inflammatory conditions or irreversible pulpitis. In the latter condition, other studies cited by the researchers have shown that FGF expression decreases while CCL11 levels increase\u2014a pattern that is now beginning to make more sense.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The primary teeth that were once simply placed beneath a pillow while children waited for a visit from the tooth fairy may, in fact, contain biomolecules that could one day become part of future regenerative therapies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Source DOI: <a href=\"http:\/\/10.3892\/etm.2021.10791\">http:\/\/10.3892\/etm.2021.10791<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Authors: Nanda Ayu, drg. Achmad Zam Zam Aghasy, M.Kes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Photo: Pexels<\/p>","protected":false},"excerpt":{"rendered":"<p>Sel punca dari pulpa gigi susu anak-anak ternyata menyimpan mekanisme molekuler yang jauh lebih kompleks dari yang dibayangkan. Sebuah studi yang dipublikasikan di Experimental and Therapeutic Medicine (2021) mengungkap temuan mengejutkan: fibroblast growth factor 2 (FGF2), faktor pertumbuhan yang selama ini dikenal sebagai pemain utama dalam perkembangan gigi dan perbaikan dentin, ternyata mampu menekan ekspresi [&hellip;]<\/p>\n","protected":false},"author":615,"featured_media":20613,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[359,136,326,318,316,317,321],"tags":[298,307,289,291,297],"class_list":["post-20609","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-artikel","category-berita-terbaru","category-sdg-10","category-sdg-17","category-sdg-3","category-sdg-4","category-sdg-9","tag-sdg-10-mengurangi-ketidaksetaraan","tag-sdg-17-kemitraan-untuk-mencapai-tujuan","tag-sdg-3-kesehatan-dan-kesejahteraan-yang-baik","tag-sdg-4-pendidikan-berkualitas","tag-sdg-9-industri-inovasi-dan-infrastruktur"],"gutentor_comment":0,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan - Fakultas Kedokteran Gigi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fkg.ugm.ac.id\/en\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan - Fakultas Kedokteran Gigi\" \/>\n<meta property=\"og:description\" content=\"Sel punca dari pulpa gigi susu anak-anak ternyata menyimpan mekanisme molekuler yang jauh lebih kompleks dari yang dibayangkan. Sebuah studi yang dipublikasikan di Experimental and Therapeutic Medicine (2021) mengungkap temuan mengejutkan: fibroblast growth factor 2 (FGF2), faktor pertumbuhan yang selama ini dikenal sebagai pemain utama dalam perkembangan gigi dan perbaikan dentin, ternyata mampu menekan ekspresi [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fkg.ugm.ac.id\/en\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/\" \/>\n<meta property=\"og:site_name\" content=\"Fakultas Kedokteran Gigi\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/p\/Fakultas-Kedokteran-Gigi-UGM-100075927681679\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-07-17T03:50:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-17T03:50:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/fkg.ugm.ac.id\/wp-content\/uploads\/sites\/30\/2026\/07\/pexels-alex-green-5692270-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1648\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"achmadzamzamaghasy\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"achmadzamzamaghasy\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/\"},\"author\":{\"name\":\"achmadzamzamaghasy\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#\\\/schema\\\/person\\\/5e527b2939dff262f173d10f32d2638a\"},\"headline\":\"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan\",\"datePublished\":\"2026-07-17T03:50:51+00:00\",\"dateModified\":\"2026-07-17T03:50:53+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/\"},\"wordCount\":694,\"publisher\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/wp-content\\\/uploads\\\/sites\\\/30\\\/2026\\\/07\\\/pexels-alex-green-5692270-scaled.jpg\",\"keywords\":[\"SDG 10: Mengurangi Ketidaksetaraan\",\"SDG 17: Kemitraan untuk mencapai Tujuan\",\"SDG 3: Kesehatan dan Kesejahteraan yang Baik\",\"SDG 4: Pendidikan Berkualitas\",\"SDG 9: Industri, Inovasi dan Infrastruktur\"],\"articleSection\":[\"Artikel\",\"Berita Terbaru\",\"SDG 10\",\"SDG 17\",\"SDG 3\",\"SDG 4\",\"SDG 9\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/\",\"url\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/\",\"name\":\"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan - Fakultas Kedokteran Gigi\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/wp-content\\\/uploads\\\/sites\\\/30\\\/2026\\\/07\\\/pexels-alex-green-5692270-scaled.jpg\",\"datePublished\":\"2026-07-17T03:50:51+00:00\",\"dateModified\":\"2026-07-17T03:50:53+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/#primaryimage\",\"url\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/wp-content\\\/uploads\\\/sites\\\/30\\\/2026\\\/07\\\/pexels-alex-green-5692270-scaled.jpg\",\"contentUrl\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/wp-content\\\/uploads\\\/sites\\\/30\\\/2026\\\/07\\\/pexels-alex-green-5692270-scaled.jpg\",\"width\":2560,\"height\":1648},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#website\",\"url\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/\",\"name\":\"Fakultas Kedokteran Gigi\",\"description\":\"Universitas Gadjah Mada\",\"publisher\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#organization\",\"name\":\"Fakultas Kedokteran Gigi\",\"url\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/wp-content\\\/uploads\\\/sites\\\/30\\\/2024\\\/05\\\/Group.png\",\"contentUrl\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/wp-content\\\/uploads\\\/sites\\\/30\\\/2024\\\/05\\\/Group.png\",\"width\":248,\"height\":257,\"caption\":\"Fakultas Kedokteran Gigi\"},\"image\":{\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/p\\\/Fakultas-Kedokteran-Gigi-UGM-100075927681679\\\/\",\"https:\\\/\\\/www.instagram.com\\\/fkgugm\\\/?igshid=MTNiYzNiMzkwZA\",\"https:\\\/\\\/www.youtube.com\\\/@ugmfkg2266\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/id\\\/#\\\/schema\\\/person\\\/5e527b2939dff262f173d10f32d2638a\",\"name\":\"achmadzamzamaghasy\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/703457fd59defa6504a99ae1c5e493d7e564bb3bac4c47b8ce9215cbfb298e36?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/703457fd59defa6504a99ae1c5e493d7e564bb3bac4c47b8ce9215cbfb298e36?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/703457fd59defa6504a99ae1c5e493d7e564bb3bac4c47b8ce9215cbfb298e36?s=96&d=mm&r=g\",\"caption\":\"achmadzamzamaghasy\"},\"url\":\"https:\\\/\\\/fkg.ugm.ac.id\\\/en\\\/author\\\/achmadzamzamaghasy\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan - Fakultas Kedokteran Gigi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/fkg.ugm.ac.id\/en\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/","og_locale":"en_US","og_type":"article","og_title":"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan - Fakultas Kedokteran Gigi","og_description":"Sel punca dari pulpa gigi susu anak-anak ternyata menyimpan mekanisme molekuler yang jauh lebih kompleks dari yang dibayangkan. Sebuah studi yang dipublikasikan di Experimental and Therapeutic Medicine (2021) mengungkap temuan mengejutkan: fibroblast growth factor 2 (FGF2), faktor pertumbuhan yang selama ini dikenal sebagai pemain utama dalam perkembangan gigi dan perbaikan dentin, ternyata mampu menekan ekspresi [&hellip;]","og_url":"https:\/\/fkg.ugm.ac.id\/en\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/","og_site_name":"Fakultas Kedokteran Gigi","article_publisher":"https:\/\/www.facebook.com\/p\/Fakultas-Kedokteran-Gigi-UGM-100075927681679\/","article_published_time":"2026-07-17T03:50:51+00:00","article_modified_time":"2026-07-17T03:50:53+00:00","og_image":[{"width":2560,"height":1648,"url":"https:\/\/fkg.ugm.ac.id\/wp-content\/uploads\/sites\/30\/2026\/07\/pexels-alex-green-5692270-scaled.jpg","type":"image\/jpeg"}],"author":"achmadzamzamaghasy","twitter_card":"summary_large_image","twitter_misc":{"Written by":"achmadzamzamaghasy","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/#article","isPartOf":{"@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/"},"author":{"name":"achmadzamzamaghasy","@id":"https:\/\/fkg.ugm.ac.id\/id\/#\/schema\/person\/5e527b2939dff262f173d10f32d2638a"},"headline":"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan","datePublished":"2026-07-17T03:50:51+00:00","dateModified":"2026-07-17T03:50:53+00:00","mainEntityOfPage":{"@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/"},"wordCount":694,"publisher":{"@id":"https:\/\/fkg.ugm.ac.id\/id\/#organization"},"image":{"@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/#primaryimage"},"thumbnailUrl":"https:\/\/fkg.ugm.ac.id\/wp-content\/uploads\/sites\/30\/2026\/07\/pexels-alex-green-5692270-scaled.jpg","keywords":["SDG 10: Mengurangi Ketidaksetaraan","SDG 17: Kemitraan untuk mencapai Tujuan","SDG 3: Kesehatan dan Kesejahteraan yang Baik","SDG 4: Pendidikan Berkualitas","SDG 9: Industri, Inovasi dan Infrastruktur"],"articleSection":["Artikel","Berita Terbaru","SDG 10","SDG 17","SDG 3","SDG 4","SDG 9"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/","url":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/","name":"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan - Fakultas Kedokteran Gigi","isPartOf":{"@id":"https:\/\/fkg.ugm.ac.id\/id\/#website"},"primaryImageOfPage":{"@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/#primaryimage"},"image":{"@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/#primaryimage"},"thumbnailUrl":"https:\/\/fkg.ugm.ac.id\/wp-content\/uploads\/sites\/30\/2026\/07\/pexels-alex-green-5692270-scaled.jpg","datePublished":"2026-07-17T03:50:51+00:00","dateModified":"2026-07-17T03:50:53+00:00","breadcrumb":{"@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/#primaryimage","url":"https:\/\/fkg.ugm.ac.id\/wp-content\/uploads\/sites\/30\/2026\/07\/pexels-alex-green-5692270-scaled.jpg","contentUrl":"https:\/\/fkg.ugm.ac.id\/wp-content\/uploads\/sites\/30\/2026\/07\/pexels-alex-green-5692270-scaled.jpg","width":2560,"height":1648},{"@type":"BreadcrumbList","@id":"https:\/\/fkg.ugm.ac.id\/ketika-pulpa-gigi-susu-menyimpan-kunci-regenerasi-jaringan\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/fkg.ugm.ac.id\/"},{"@type":"ListItem","position":2,"name":"Ketika Pulpa Gigi Susu Menyimpan Kunci Regenerasi Jaringan"}]},{"@type":"WebSite","@id":"https:\/\/fkg.ugm.ac.id\/id\/#website","url":"https:\/\/fkg.ugm.ac.id\/id\/","name":"Faculty of Dentistry","description":"Universitas Gadjah Mada","publisher":{"@id":"https:\/\/fkg.ugm.ac.id\/id\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/fkg.ugm.ac.id\/id\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/fkg.ugm.ac.id\/id\/#organization","name":"Faculty of Dentistry","url":"https:\/\/fkg.ugm.ac.id\/id\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/fkg.ugm.ac.id\/id\/#\/schema\/logo\/image\/","url":"https:\/\/fkg.ugm.ac.id\/wp-content\/uploads\/sites\/30\/2024\/05\/Group.png","contentUrl":"https:\/\/fkg.ugm.ac.id\/wp-content\/uploads\/sites\/30\/2024\/05\/Group.png","width":248,"height":257,"caption":"Fakultas Kedokteran Gigi"},"image":{"@id":"https:\/\/fkg.ugm.ac.id\/id\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/p\/Fakultas-Kedokteran-Gigi-UGM-100075927681679\/","https:\/\/www.instagram.com\/fkgugm\/?igshid=MTNiYzNiMzkwZA","https:\/\/www.youtube.com\/@ugmfkg2266"]},{"@type":"Person","@id":"https:\/\/fkg.ugm.ac.id\/id\/#\/schema\/person\/5e527b2939dff262f173d10f32d2638a","name":"achmadzamzamaghasy","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/703457fd59defa6504a99ae1c5e493d7e564bb3bac4c47b8ce9215cbfb298e36?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/703457fd59defa6504a99ae1c5e493d7e564bb3bac4c47b8ce9215cbfb298e36?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/703457fd59defa6504a99ae1c5e493d7e564bb3bac4c47b8ce9215cbfb298e36?s=96&d=mm&r=g","caption":"achmadzamzamaghasy"},"url":"https:\/\/fkg.ugm.ac.id\/en\/author\/achmadzamzamaghasy\/"}]}},"_links":{"self":[{"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/posts\/20609","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/users\/615"}],"replies":[{"embeddable":true,"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/comments?post=20609"}],"version-history":[{"count":1,"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/posts\/20609\/revisions"}],"predecessor-version":[{"id":20614,"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/posts\/20609\/revisions\/20614"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/media\/20613"}],"wp:attachment":[{"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/media?parent=20609"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/categories?post=20609"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fkg.ugm.ac.id\/en\/wp-json\/wp\/v2\/tags?post=20609"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}